abstract：:Recently, the enzyme cyclooxygenase (COX) has been recognized to exist as constitutive (COX-1) and inducible isoforms (COX-2). In previous studies, drugs that were inhibitors of both COX-1 and COX-2 failed to decrease brain edema formation or improve Neurological Severity Score (NSS) after closed head trauma (CHT), al...

journal_title：Journal of neurosurgical anesthesiology

authors： Koyfman L,Kaplanski J,Artru AA,Talmor D,Rubin M,Shapira Y

更新日期：2000-01-01 00:00:00

abstract：:During the past 5 years, the surgical repair for sagittal synostosis has been modified to a more complex and involved procedure. This led to a retrospective evaluation of the current transfusion practice in a large series of craniosynostosis repairs. The charts of 76 patients (81 surgical procedures) undergoing cranio...

journal_title：Journal of neurosurgical anesthesiology

authors： Faberowski LW,Black S,Mickle JP

更新日期：1999-07-01 00:00:00

abstract：:In this article anesthesiologic and hematologic aspects of a patient with Hemophilia-A, who underwent craniotomy for a right middle cerebral artery aneurysm, are discussed. ...

journal_title：Journal of neurosurgical anesthesiology

authors： Dönmez A,Türker H,Sekerci S,Kayhan Z,Ozbek N

更新日期：1999-07-01 00:00:00

abstract：:We describe a case of subarachnoid hemorrhage (SAH) complicated by acute respiratory distress syndrome (ARDS) and cerebral vasospasm. Inhaled nitric oxide (NO) was used to improve oxygenation, thereby facilitating cerebral aneurysm clipping. ...

journal_title：Journal of neurosurgical anesthesiology

authors： Grady RE,Strickland RA,Fabi AY,Murray MJ

更新日期：1999-04-01 00:00:00

abstract：:In patients with lesions of the cervical spine, direct laryngoscopy for endotracheal intubation entails the risk of injuring the spinal cord. In an attempt to avoid this complication, the authors used flexible fiberoptic nasal intubation in a series of 327 patients with cervical lesions undergoing elective neurosurgic...

journal_title：Journal of neurosurgical anesthesiology

authors： Fuchs G,Schwarz G,Baumgartner A,Kaltenböck F,Voit-Augustin H,Planinz W

更新日期：1999-01-01 00:00:00

abstract：:Thiopental intravenous injections before temporary clipping and mild hypothermia have protective effects in the setting of cerebral ischemia, and are used clinically in some centers. However, it is not known whether mild hypothermia affects thiopental-induced electroencephalogram (EEG) burst suppression. In this study...

journal_title：Journal of neurosurgical anesthesiology

authors： Kim JH,Kim SH,Yoo SK,Kim JY,Nam YT

更新日期：1998-07-01 00:00:00

abstract：:This report describes a sudden decrease in blood pressure after conservative treatment of acute intracranial hypertension. A 63-year-old woman with acute hydrocephalus after undergoing clipping of an aneurysm of the right supracerebellar artery developed increased intracranial pressure, necessitating surgical manageme...

journal_title：Journal of neurosurgical anesthesiology

authors： Inoue S,Ninaga H,Kawaguchi M,Furuya H

更新日期：1998-04-01 00:00:00

abstract：:Studies on cerebral blood flow during hypotension and high intracranial pressure are scarce. Accordingly, this study examines the effects of increased cerebrospinal fluid (CSF) pressure on the cerebral circulatory response to hemorrhage. Measurements of cerebral microcirculation with laser Doppler flowmetry was perfor...

journal_title：Journal of neurosurgical anesthesiology

authors： Rise IR,Risöe C,Kirkeby OJ

更新日期：1998-01-01 00:00:00

abstract：:Because deliberate hypothermia is becoming commonly used during neurosurgery, this study was performed to investigate the effects of a progressive reduction of body core temperature (T) on whole body oxygenation variables in patients undergoing elective intracranial surgery. In 13 patients (Hypothermic Group), T was r...

journal_title：Journal of neurosurgical anesthesiology

authors： Bacher A,Illievich UM,Fitzgerald R,Ihra G,Spiss CK

更新日期：1997-07-01 00:00:00

abstract：:We present a retrospective review of the perioperative management and complications of 102 cases of acoustic neuroma operated on at an English teaching hospital over the last 9 years. Nine patients had a bulbar palsy postoperatively; five of those patients developed pulmonary complications. A bulbar palsy was more lik...

journal_title：Journal of neurosurgical anesthesiology

authors： Duane DT,Howard SJ,Kraayenbrink M

更新日期：1997-07-01 00:00:00

abstract：:The aim of this study was to determine the influence of acute and chronic ethanol treatment on neurological outcome following head trauma in rats. Eight-two Sprague-Dawley rats were divided into 10 groups. Four groups received sham head trauma (surgical incision of the scalp but no trauma) and were treated with (A) no...

journal_title：Journal of neurosurgical anesthesiology

authors： Shapira Y,Lam AM,Paez A,Artru AA,Laohaprasit V,Donato T

更新日期：1997-04-01 00:00:00

abstract：:Acute respiratory distress syndrome is commonly encountered in head-injured patients. Positive and expiratory pressure (PEEP) is useful in improving oxygenation. However, PEEP, by increasing intrathoracic pressure, decreases venous return, mean arterial pressure, and cardiac output and increases jugular vein pressure....

journal_title：Journal of neurosurgical anesthesiology

authors： Feldman Z,Robertson CS,Contant CF,Gopinath SP,Grossman RG

更新日期：1997-04-01 00:00:00

abstract：:In a rat model of middle cerebral artery occlusion (MCAo) and reperfusion (120 min), previous studies have demonstrated that hemodilution with molecular hemoglobin decreases ischemic brain injury. However, long-term recovery data on the therapeutic efficacy of molecular hemoglobin for cerebral ischemia are lacking. Ac...

journal_title：Journal of neurosurgical anesthesiology

authors： Cole DJ,Drummond JC,Patel PM,Reynolds LR

更新日期：1997-01-01 00:00:00

abstract：:The purpose of this study was to evaluate arterial blood pressure and middle cerebral artery blood flow velocity in children during induction of anesthesia with sevoflurane. These measures were compared to findings in a control group anesthetized with halothane. Each child received mask induction of sevoflurane (n = 9...

journal_title：Journal of neurosurgical anesthesiology

authors： Berkowitz RA,Hoffman WE,Cunningham F,McDonald T

更新日期：1996-07-01 00:00:00

abstract：:A case of pseudoobstruction of the colon in a patient receiving oral nimodipine therapy is presented. Early recognition of this entity, diagnostic aids, and therapy are discussed. Successful colonoscopic decompression and close observation allowed completion of nimodipine course of therapy. ...

journal_title：Journal of neurosurgical anesthesiology

authors： Fahy BG

更新日期：1996-04-01 00:00:00

abstract：:Cerebral air embolism occurred in a patient undergoing posterior fossa surgery performed in the sitting position for acoustic neuroma removal. The patient experienced two episodes of venous air embolism, as evidenced by precordial Doppler, end-tidal carbon dioxide reduction, and oxygen desaturation. In both cases, air...

journal_title：Journal of neurosurgical anesthesiology

authors： Tommasino C,Rizzardi R,Beretta L,Venturino M,Piccoli S

更新日期：1996-01-01 00:00:00

abstract：:To reduce the incidence of neurological and neuropsychological dysfunction following hypothermic cardiopulmonary bypass (CPB), central nervous system (CNS) monitoring before, during, and after CPB seems to be necessary. Compared to the total scope of hemodynamic monitoring CNS monitoring, however, is mostly investigat...

journal_title：Journal of neurosurgical anesthesiology

authors： Gombotz H

更新日期：1995-10-01 00:00:00

abstract：:We report our experience with anesthetic care for six patients with pseudoankylosis of the mandible following neurosurgical procedures, four of whom required fiberoptically guided intubation for anesthesia. We suggest that the development of operative approaches and reconstruction techniques in skull base surgery may ...

journal_title：Journal of neurosurgical anesthesiology

authors： Kawaguchi M,Sakamoto T,Ohnishi H,Karasawa J,Furuya H

更新日期：1995-07-01 00:00:00

abstract：:The relationship between intracranial pressure and arterial blood pressure during sevoflurane or halothane anesthesia was evaluated in New Zealand white rabbits after cryogenic brain injury. Fourteen rabbits were randomized to be anesthetized with 1.5 MAC of sevoflurane or halothane in oxygen. All animals were paralyz...

journal_title：Journal of neurosurgical anesthesiology

authors： Kim HK,Zornow MH,Illievich UM,Strnat MA,Scheller MS

更新日期：1994-10-01 00:00:00

abstract：:Clearance of valproic acid from brain tissue is believed to occur via a carrier-mediated system(s). The present study was designed to determine whether clearance was capacity-limited (saturable) and whether it occurred primarily at the choroid plexus. Ten rabbits were anesthetized with halothane and surgically prepare...

journal_title：Journal of neurosurgical anesthesiology

authors： Artru AA,Adkinson KD,Powers KM,Shen DD

更新日期：1994-07-01 00:00:00

abstract：:Episodes of arterial hypotension are associated with an increased mortality in head injury patients. Rapid infusion of sodium bicarbonate in such patients may cause hypotension and elevate intracranial pressure. Therefore, we examined the effects of tromethamine (THAM) versus bicarbonate on intracranial pressure and b...

journal_title：Journal of neurosurgical anesthesiology

authors： Duthie SE,Goulin GD,Zornow MH,Scheller MS,Peterson BM

更新日期：1994-07-01 00:00:00

abstract：:The effect of the calcium blocker nimodipine on the cerebral blood flow (CBF) and cerebral autoregulatory responses was examined in seven fentanyl/N2O/anesthetized pigs. CBF was measured continuously from the sagittal sinus by a venous outlet flow technique. Cerebral autoregulation tests were performed before, after 3...

journal_title：Journal of neurosurgical anesthesiology

authors： Stånge K,Lagerkranser M,Sollevi A

更新日期：1994-04-01 00:00:00

abstract：:This study was designed to investigate the incidence and clinical consequences of hemidiaphragmatic paresis in patients undergoing carotid endarterectomy using cervical plexus block anesthesia. In 28 patients, diaphragmatic motion was evaluated by fluoroscopy 20 min after cervical plexus block with 1% mepivacaine. In ...

journal_title：Journal of neurosurgical anesthesiology

authors： Castresana MR,Masters RD,Castresana EJ,Stefansson S,Shaker IJ,Newman WH

更新日期：1994-01-01 00:00:00

abstract：:Although cerebral monitoring during CPB remains primarily investigational, recent data support its clinical utility. In particular, it is cerebral metabolic monitoring that provides meaningful information in terms of preparing the brain for dhCPB and dhCA. Cerebral blood flow or cerebral blood flow velocity monitoring...

journal_title：Journal of neurosurgical anesthesiology

authors： Kern FH,Schell RM,Greeley WJ

更新日期：1993-07-01 00:00:00

abstract：:Translocation of cerebrospinal fluid (CSF) between the intracranial and spinal subarachnoid space was blocked by ligating the cervical spinal core in eight cats under pentobarbital and nitrous oxide anesthesia, and the effects of cerebral venous congestion on the pressure-volume index (PVI), a measure relating the cha...

journal_title：Journal of neurosurgical anesthesiology

authors： Kotani J,Adachi R,Fujita N,Sugioka S,Ueda Y

更新日期：1993-04-01 00:00:00

abstract：:A case of two incidental familial intracranial aneurysms associated with asymptomatic coarctation of the aorta is reported. Priority was assigned to aneurysm surgery, which was accomplished by means of two distinct procedures, both requiring moderate, deliberate hypotension. Invasive monitoring always included radial ...

journal_title：Journal of neurosurgical anesthesiology

authors： Orsi P,Rosa G,Liberatori G,Lunardi PP,Ferrante L

更新日期：1993-01-01 00:00:00

abstract：:Cerebral blood flow measurements using a thermal diffusion technique were made in conjunction with an extensive cardiovascular evaluation, during and after administration of intravenous labetalol given for blood pressure control in craniotomy patients. Eighteen patients, ages 30-65 years, ASAII and III, scheduled for ...

journal_title：Journal of neurosurgical anesthesiology

authors： Dubois M,Caputy A,MacCosbe P,Lea D,Duma C

更新日期：1992-07-01 00:00:00

abstract：:This experiment was designed to study the effect of progressively increasing blood propofol concentrations on cerebral blood flow (CBF), cerebral metabolic rate for oxygen (CMRO2), and the electroencephalogram (EEG). Nine New Zealand White rabbits were anesthetized with morphine (10 mg kg bolus and 2 mg/kg/h infusion)...

journal_title：Journal of neurosurgical anesthesiology

authors： Ramani R,Todd MM,Warner DS

更新日期：1992-04-01 00:00:00

abstract：:The affect of L-644,711, an anion transport inhibitor, on ischemic brain injury and edema was investigated. Spontaneously hypertensive rats were given one of the following doses of intrathecal L-644,711 during 180 min of middle cerebral artery occlusion and 120 min of reperfusion: control, vehicle only; dose I, 100 mi...

journal_title：Journal of neurosurgical anesthesiology

authors： Cole DJ,Ghazal EA,Osborne TN

更新日期：1991-12-01 00:00:00

abstract：:Motor evoked potentials (MEPs) after transcranial magnetic stimulation (TMS) have been examined in 12 monkeys under neuroleptanalgesia (NLA). Compound muscle action potentials were recorded from abductor policis brevis (APB) and gastroncnemius (GN) muscles contralateral to the stimulation site. After obtaining baselin...

journal_title：Journal of neurosurgical anesthesiology

authors： Ghaly RF,Stone JL,Levy WJ,Kartha R,Brunner EA,Aldrete JA,Laege R

更新日期：1991-06-01 00:00:00

abstract：:Intraoperative brain surface electrocorticography (ECoG) is an integral part of the surgical excision of epileptogenic foci. If surgical excision is performed under general anesthesia, anesthetics should be selected that do not seriously interfere with the ECoG. We report a case where nitrous oxide appeared to suppres...

journal_title：Journal of neurosurgical anesthesiology

authors： Artru AA,Lettich E,Colley PS,Ojemann GA

更新日期：1990-09-01 00:00:00

abstract：:The influence of isoflurane-induced hypotension on regional cerebral blood flow (rCBF) and cerebrovascular autoregulation was evaluated in 11 normocapnic pigs during anesthesia comprising fentanyl and nitrous oxide in oxygen. rCBF was determined as sagittal sinus outflow and recorded continuously by an electromagnetic...

journal_title：Journal of neurosurgical anesthesiology

authors： Stånge K,Lagerkranser M,Sollevi A

更新日期：1990-06-01 00:00:00

abstract：:The effects of PaCO2 and mean arterial pressure (MAP) on succinylcholine-induced changes in cerebrospinal fluid (CSF) pressure were examined in 31 dogs anesthetized with halothane (0.7% end-expired) and nitrous oxide (66% inspired) in oxygen. Group 1 (n = 9) received succinylcholine (1.5 mg/kg i.v.) without control of...

journal_title：Journal of neurosurgical anesthesiology

authors： Artru AA

更新日期：1990-03-01 00:00:00

abstract：:The function of the central nervous system-and other organs-depends upon preservation of ionic gradients across cell membranes. In nervous tissue, the ion gradients are especially important since generation of action potentials and synaptic processes relies on transfer of ions across the plasma membrane. This report d...

journal_title：Journal of neurosurgical anesthesiology

authors： Hansen AJ,Lundbaek JA

更新日期：1989-12-01 00:00:00

abstract：:The effects of flumazenil (a benzodiazepine antagonist) on autoregulation of cerebral blood flow (CBF) were examined in dogs receiving midazolam and in dogs not receiving midazolam. Both groups were anesthetized with halothane (0.3% end-expired) and nitrous oxide (66%) in oxygen. Auto-regulation of CBF was assessed by...

journal_title：Journal of neurosurgical anesthesiology

authors： Artru AA

更新日期：1989-09-01 00:00:00

abstract：:It has been suggested that N2O may alter the sensitivity of the brain to ischemia. To test this hypothesis. we examined the effects of N2O on the development of left-right hemispheric asymmetry in the electroencephalogram (EEG) during hemorrhagic hypotension in rats subjected to unilateral carotid occlusion. Rats were...

journal_title：Journal of neurosurgical anesthesiology

authors： Zhou JG,Todd MM,Warner DS,Loftus CM

更新日期：1989-06-01 00:00:00

abstract：:The thromboxane receptor antagonist SQ29548 was administered to mongrel dogs after an 11-min period of global cerebral ischemia to test the hypothesis that it would improve delayed postischemic cerebral hypoperfusion (PIH) during concurrent elevations in cerebral venous thromboxane B2 (TxB2), the stable metabolite of ...

journal_title：Journal of neurosurgical anesthesiology

authors： Olympio MA,Whitley JM,Prough DS

更新日期：1989-03-01 00:00:00